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. 2022 Jan 5;36(2):328–340. doi: 10.1038/s41433-021-01807-4

Fig. 1. Structure of human Leucine-rich α-2 glycoprotein 1 (LRG1).

Fig. 1

A LRG1 is a 312 aa protein containing eight leucine-rich repeats (LRR), evolutionarily associated with protein–protein interaction, four N-linked and one O-linked glycosylation sites and two disulphide bonds. Following processing of the N-terminal signal peptide, the mature 50 kDa form of LRG1 is released into the extracellular space. B ALPHAFOLD2 prediction of LRG1 structure by deep learning algorithm [147]. β-sheet in green, helix in red.