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. 2022 Jan 19;12:770652. doi: 10.3389/fphar.2021.770652

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Copyright © 2022 Zhang, Niu, Ma, Chen, Wen, Li, Zhou, Deng, Shi, Pu, Yang, Wang, Zou, Chen and Ma.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Fenofibrate attenuates lipid accumulation in HFD-fed mice. (A) The levels of SCD-1 were measured by western blotting after 14 weeks. Representative western blots are shown. These results are means ± SD (n = 5–8 mice/group). **p < 0.01, ****p < 0.0001, HFD group versus control group, or fenofibrate + HFD-fed group versus HFD group. (B) Serum triglyceride (TG) levels and (C) hepatic TG levels. These results are means ± SD (n = 10). *p < 0.05, **p < 0.01, ****p < 0.0001, HFD group versus control group, or fenofibrate + HFD-fed group versus HFD group.