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. 2022 Jan 19;12:818227. doi: 10.3389/fphar.2021.818227

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Copyright © 2022 He, Hu, Liu, Zhu, Zhang, You, Shao, Li, Zhang, Cui, He, Ge and Yang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The comparison of anti-lipid accumulation in different concentration of POL and four flavonoids from POL. L02 cells were incubated with 300 μM FFA (oleic acid: palmitic acid = 2: 1) and treated with different concentrations of POL and 20 μM myricetin, luteolin, kaempferol, and apigenin for 24 h, respectively. Lipid accumulation and content of TG were evaluated by oil red O staining (A) and enzymatic colorimetric assay (B). Comparing with model group, ***p < 0.001.