TABLE 1.
Drugs used in the treatment of Idiopathic pulmonary fibrosis (IPF).
Drugs | Mechanism of action | References |
---|---|---|
Pirfenidone | Anti-fibrotic drug | Nathan et al. (2019) |
Nintedanib | Anti-PDGFR, VEGFR, FGFR drug | Flaherty et al. (2019), Makino (2021) |
Pamrevlumab | Anti-CTGF antibody | Richeldi et al. (2020) |
GSK3008348 | αvβ6 antagonist | John et al. (2020) |
sildenafil | phosphodiesterase-5 inhibitor | Kang & Song, (2021) |
Co-trimoxazole or doxycycline | Antimicrobial drug | Wilson et al. (2020) |
Lebrikizumab | Anti-IL13 | Maher et al. (2021b) |
Carlumab | Anti-CCL2 | Raghu et al. (2015) |
Simtuzumab | Anti-LOX antibody | Raghu et al. (2017) |