Skip to main content
. 2022 Feb 1;12:48. doi: 10.1038/s41398-022-01808-1

Fig. 3. Endocannabinoid and cortisol concentrations at hospitalization and 6–8 months after injury in those with and without CAPS diagnosis of PTSD.

Fig. 3

PTSD was diagnosed at the follow-up visit using the CAPS; AEA (A), 2-AG (B), and cortisol (C) concentrations were determined in serum from blood samples collected at the time of hospitalization and at follow-up, which occurred 6–8 months following hospital discharge. Each data set was analyzed by two-way ANOVA and planned comparisons between PTSD positive and negative groups were made at each time point (i.e., hospitalization and follow-up). The ANOVA results are: AEA: Time F(1,312) = 3.42, p = 0.066; PTSD F(1,312) = 6.03, p = 0.015; Interaction F(1,312) = 0.34, p = 0.56; 2-AG: Time F(1,312) = 130, p < 0.0001; PTSD F(1,312) = 0.86, p = 0.35; Interaction F(1,312) = 3.43, p = 0.065; and cortisol: Time F(1,315) = 0.60, p = 0.44; PTSD F(1,315) = 4.03, p < 0.05; Interaction F(1,315) = 0.60, p = 0.44. Symbols represent mean and vertical lines indicate SEM. *p < 0.05; #p = 0.08, and ^p = 0.09 by Sidak’s multiple comparison test.