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. 2022 Feb 1;13:590. doi: 10.1038/s41467-022-28257-0

Fig. 7. The role of the GroP modification in GAS protection against histones and lysozyme.

Fig. 7

a, b Analysis of resistance of GAC mutants deficient in the GroP modification to a lysozyme, and b histone mixture. Data are mean values ± S.D., n = 5 biologically independent experiments in (a), n = 4 biologically independent experiments in (b). P values were calculated by two-way ANOVA with Bonferroni’s multiple comparison test. Source data for (a, b) are provided as a Source data file. c Introduction of charges to the GAS cell wall by GlcNAc deacetylation and GroP modification modulates resistance to host cationic antimicrobial proteins.