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. 2022 Feb 1;12:46. doi: 10.1038/s41398-022-01802-7

Table 2.

Best-ranked CpGs for the exposure intervention and therapy.

CpG P value Q value Bio rank Stat rank Sum rank Gene
Exposure
 cg01586609 4.3 × 10−5 0.83 53 60 113 HTR3A
 cg02279108 2.95 × 10−5 0.85 419 214 633 MNX1-AS1
 cg27120833 1.63 × 10−4 0.89 35 620 655 ARFGAP3
 cg13927247 2.2 × 10−4 0.87 448 290 738 DTWD2
 cg03002526 1.9 × 10−4 0.87 673 305 978 HACE1
 cg09855140 2.38 × 10−4 0.91 205 1044 1249 FKSG29
 cg20611272 2 × 10−4 0.86 1068 251 1319 ODF1
 cg07428959 9.7 × 10−5 0.90 445 885 1330 JADE1
 cg13857354 5.7 × 10−5 0.91 172 1219 1391 RNPEPL1
 cg13054007 2.4 × 10−4 0.87 1180 271 1451 SPRY2
Therapy
 cg01848660 1.00 × 10−4 1 124 42 166 C1D
 cg23839680 3.03 × 10−4 1 180 153 333 PSPH
 cg07205203 3.43 × 10−4 1 211 175 386 PPP1CB
 cg03308839 2.34 × 10−4 1 584 107 691 NDE1
 cg09160681 6.62 × 10−4 1 553 323 876 PARM1
 cg12594803 1.74 × 10−3 1 28 873 901 DLG1
 cg19676182 1.26 × 10−3 1 471 624 1095 CCDC149
 cg20956594 8.78 × 10−4 1 701 425 1126 POMP
 cg15210526 2.27 × 10−4 1 1054 103 1157 MPZL1
 cg25853622 1.19 × 10−3 1 699 590 1289 LPP

This Table displays the 10 best CpGs ranked according to the cumulative, statistical and biological ranking (see “Methods”) for the exposure intervention and therapy respectively. The p value column reports the p value for the effect of time in the selected model. The Q value columns reports the corresponding p value after multiple testing correction. The Gene Column reports the gene annotated to the CpG.