Table 3.
Baseline measurements and changes with treatment related to outcomes of pulmonary function and weight.
| BPAP, Mean (SD) | CPAP, Mean (SD) | Intergroup Differences† | ||||
|---|---|---|---|---|---|---|
| Baseline | 3 Months | Baseline | 3 Months | Mean (CI) | P Value | |
| ABG | ||||||
| PaCO2 (mm Hg) | 57 (8) | 44 (8)** | 52 (6) | 47 (6)* | 9.4 (4.3 to 15) | .001 |
| Bicarbonate (mmol/L) | 33 (5) | 27 (3)** | 31 (3) | 28 (3)* | 4.8 (1.8 to 7.8) | .004 |
| Spirometry | ||||||
| FEV1 (L) | 1.3 (0.6) | 1.6 (0.7) | 1.5 (0.5) | 1.6 (0.5) | −0.3 (−0.5 to −0.0) | .04 |
| FVC (L) | 2.0 (0.9) | 2.3 (0.9) | 2.6 (0.7) | 2.5 (0.6) | −0.5 (−0.9 to −0.0) | .04 |
| Weight (kg) | 125 (28) | 124 (28) | 120 (19) | 120 (19) | 2.8 (−2.0 to 7.7) | NS |
†
Adjusted for baseline values of the variables analyzed and age, sex, BMI, AHI, and FEV1. *P < .05 intragroup difference (3 months–baseline). **P < .01 intragroup difference (3 months–baseline). ABG = arterial blood gas, AHI = apnea-hypopnea index, BMI = body mass index, BPAP = bilevel positive airway pressure, CI = confidence interval, CPAP = continuous positive airway pressure, FEV1 = forced expiratory volume in 1 second, FVC = forced vital capacity, NS = not significant, SD = standard deviation.