Table 5.
Baseline measurements and changes with treatment related to outcomes of neurocognitive tests.
| BPAP, Mean (SD) | CPAP, Mean (SD) | Intergroup Differences† | ||||
|---|---|---|---|---|---|---|
| Baseline | 3 Months | Baseline | 3 Months | Mean (CI) | P Value | |
| PVT | ||||||
| Lapses | 13 (13) | 8 (13) | 5 (7) | 5 (9) | 5.5 (−2.0 to 13) | NS |
| Median: RT (ms) | 361 (97) | 315 (80) | 316 (60) | 297 (54) | 35 (−28 to 98) | NS |
| Mean slowest 10% RT (s) | 1.6 (0.7) | 2.1 (0.6)* | 2.1 (0.5) | 2.3 (0.6) | −0.4 (−0.8 to 0.0) | NS |
| Digit span forward | 7 (2) | 8 (2) | 7 (2) | 8 (2) | 0.5 (−0.8 to 1.9) | NS |
| Digit span backward | 5 (2) | 5 (2) | 5 (1) | 6 (2) | 1 (−0.8 to 2.5) | NS |
| Trail-making test | 129 (39) | 116 (42) | 134 (61) | 116 (45) | −13 (−51 to 24) | NS |
| Digit symbol substitution | 36 (12) | 39 (16) | 35 (10) | 40 (11) | −0.4 (−8.0 to 7.2) | NS |
†
Adjusted for baseline values of the variables analyzed and age, sex, BMI, AHI, and FEV1. *P < .05 intragroup difference (3 months–baseline). AHI = apnea-hypopnea index, BMI = body mass index, BPAP = bilevel positive airway pressure, CI = confidence interval, CPAP = continuous positive airway pressure, FEV1 = forced expiratory volume in 1 second, NS = not significant, PVT = psychomotor vigilance test, RT = reaction time, SD = standard deviation.