Table 3.
Leg movement activity during sleep parameters in MS patients without and with RLS.
| MS patients (n = 40) |
MS with RLS (n = 17) |
Student’s t-Test | Effect Size | ||||
|---|---|---|---|---|---|---|---|
| Mean | SD | Mean | SD | t-Value | P ≤ | Cohen’s d | |
| PLMS index | 8.5 | 14.54 | 15.2 | 15.17 | −1.577 | NS | −0.453 |
| SILMS index | 3.1 | 2.64 | 7.2 | 6.16 | −3.541 | .00082* | −0.865a |
| ISOLMS index | 9.3 | 4.59 | 12.7 | 4.12 | −2.668 | .01 | −0.790 |
| Total LMS index | 20.9 | 17.51 | 35.1 | 19.44 | −2.723 | .0086 | −0.771 |
| Bilateral PLMS, % | 38.8 | 58.55 | 18.0 | 17.76 | 1.383 | NS | 0.482 |
| Periodicity index | 0.225 | 0.255 | 0.362 | 0.228 | −1.909 | NS | −0.566 |
| PLMS duration, s | 2.1 | 0.83 | 2.2 | 0.92 | −0.434 | NS | −0.132 |
| SILMS duration, s | 2.2 | 1.09 | 2.0 | 0.51 | 0.784 | NS | 0.255 |
| ISOS duration, s | 2.4 | 0.75 | 2.1 | 0.65 | 1.483 | NS | 0.441 |
| PLMS index in REM sleep | 7.3 | 19.26 | 9.8 | 11.85 | −0.493 | NS | −0.155 |
| PLMS index in NREM sleep | 8.9 | 14.96 | 16.9 | 17.35 | −1.757 | NS | −0.493 |
*
Significant after Bonferroni correction. aEffect size value > 0.8 (large effect). MS = multiple sclerosis, NS = not significant, RLS = restless legs syndrome, PLMS = periodic leg movements during sleep, SILMS = short-interval leg movements during sleep, ISOLMS = isolated leg movements during sleep, LMS = leg movements during sleep.