Figure 1.

Construction of human corneal endothelium atlas by scRNA-seq

(A) Flowchart of the experiments performed in this study. (B) t-SNE clustering of human corneal endothelial cells colored by 4 distinct clusters. (C) Heatmap for expression of differentially expressed genes (DEGs) in each subtype. (D) Representative GO terms of all DEGs in each cell type. (E) Expression of representative marker genes across clusters. (F) Definition and surface phenotype of “effector cells.” (G) Expression of top markers in “effector cells.” (H) Representative novel markers of C1–C3 cells.