Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
MET signaling adaptors and mediators, as well as signaling pathways are depicted. Therapeutic intervention strategies to block and inhibit MET receptor oncogenic signaling cascade include blocking ligand-receptor interaction, preventing receptor dimerization, blocking MET kinase intrinsic activity, and inhibiting specific downstream signal transducers. DAG, diacylglycerol; HGF, hepatocyte growth factor; IP3, inositol triphosphate; PIP3, phosphatidylinositol (3,4,5)-triphosphate.
