Table 5.
Relationships between immunohistochemistry markers and sensitivity to targeted and other drugs.
| AFP | CK7 | GPC-3 | HepPar-1 | Ki-67 | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| χ 2 | P | χ 2 | P | χ 2 | P | χ 2 | P | χ 2 | P | |
| Sorafenib | 0.187 | 0.666 | 1.218 | 0.270 | 0.759 | 0.384 | 1.499 | 0.221 | 0.165 | 0.684 |
| Bortezomib | 1.000 | 0.572 | 0.449 | 1.000 | 0.525 | 0.550 | ||||
| Romidepsin | 0 | 1.000 | 1.895 | 0.169 | 0.000 | 0.994 | 0.002 | 0.969 | 0.013 | 0.908 |
| Ixazomib | 3.260 | 0.071 | 1.947 | 0.163 | 0.206 | 0.650 | 0.138 | 0.711 | 1.315 | 0.252 |
| Cabozantinib | 1.000 | 0.525 | 0.033 | 0.525 | 0.505 | |||||
| Regorafenib | — | — | — | — | — | — | — | — | — | — |
| Lenvatinib | 1.000 | 1.000 | 0.188 | 1.000 | 0.294 | |||||
| Sirolimus | 0.658 | 0.417 | 0 | 1.000 | 0 | 1.000 | 0.106 | 0.745 | 0 | 1.000 |
| Apatinib | 1.000 | 1.000 | 0.188 | 1.000 | 0.294 | |||||
| Carfilzomib | 0.307 | 0.580 | 0.550 | 0.458 | 1.169 | 0.280 | 0.080 | 0.777 | 0.009 | 0.925 |
| Disulfiram | 0.016 | 0.898 | 2.468 | 0.116 | 0.575 | 0 | 1.000 | 1.102 | 0.294 | |