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Endotype classification of ICU patients. (a) Heatmap depicting GSVA enrichment statistics in ICU patients (n = 82) for each endotype signature. Each 200-gene endotype was significantly upregulated in the patients classified to the endotype for which it defines. (b) Selected clinical symptomology and outcomes for predicted endotypes; Dunn's Posthoc test indicated by: # p < 0.05 cf. IHD; * p < 0·05 cf. IFN; ^ p < 0·05 cf. INF. (c) Kaplan-Meier curves describing 28-day mortality.
