Fig.1.
HSC niche players in BM.
Various cell types have been identified as components of HSC niche. Emerging evidences highlight the stromal cells in the vicinity of bone marrow vasculature such as NG2-expressing peri-arteriolar cells and LepR-expressing peri-sinusoidal stromal cells. Mature blood cell types, macrophages, adipocytes, and megakaryocytes also contribute to HSC maintenance or mobilization.