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. 2020 Jun 9;13(1 Suppl):818S–828S. doi: 10.1177/1947603520932199

Figure 4.

Figure 4.

Immunohistochemical (IHC) staining of FAM20B in the articular cartilage of control, Kashin-Beck disease (KBD), and osteoarthritis (OA) groups. In all 3 layers of OA and KBD groups, the positive staining rates in KBD and OA group were significantly lower compared with the control group. In the negative control group, no nonspecific immunostaining or background reactivity was observed. *P < 0.05; **P < 0.01; ***P < 0.01; scale bar 20 μm.