Table 1.
Characteristics of Included Studies (n = 13).
| Authors, Year | MINORS Score, % | Level of Evidence | Procedure | Outcome Measures Reported | No. of Tibias (M/F) | Lesion Location | Lesion Size | Lesion Etiology | Age (y) | Follow-up (mo) |
|---|---|---|---|---|---|---|---|---|---|---|
| Bakay et al., 1998 | 63 | RCS, level IV | OCA | XR | 5 (NR) | NR | Unicondylar | Posttraumatic | 48 (21-64) a | 19 (10-38) a |
| Drexler et al., 2015 | 75 | RCS, level IV | OCA + DFO | KS-F, KSKS | 27 (12 M/15 F) | 27 LTP | Unicondylar | Posttraumatic | 42 (17-62) | 156 (24-372) |
| Fanceshchi et al., 2008 | 75 | RCS, level IV | ACI + HTO | IKDC, Lysholm, Tegner, VAS | 8 (4 M/4 F) | 8 MTP | 3 cm2 (2-4) | NR | 49 (42-58) | 28 (25-31) |
| Gracitelli et al., 2017 | 75 | RCS, level IV | OCA | IKDC, KS-F, Modified Merle d’Aubigné-Postel | 29 (NR) | 6 MTP, 23 LTP | 14 cm2 (2-33) a | Posttraumatic | 34 (16-54) a | 69.6 (22.8-283.2) |
| Hangody et al., 2010 | 69 | PCS, level IV | OATS | Modified HSS | 16 (NR) | 15 LTP, 1 MTP | 1 cm2 (1-2) | NR | 24 (14-49) | 115.2 (24-204) |
| Kon et al., 2014 | 81 | PCS, level IV | OCS | IKDC, Tegner, Subjective | 11 (6 M/5 F) | NR | 5 cm2 (3-12) | 10 posttraumatic, 1 DIC | 37 ± 11.0 | 24 |
| Kreuz et al., 2006 | 81 | PCS, level IV | Microfracture | Cincinnati, ICRS, MRI | 11 (3 M/8 F) | NR | 2 cm2 (1-4) | NR | 39 (22-55) | 36 |
| Locht et al., 1984 | 63 | RCS, level IV | OCA | Subjective, ROM, XR | 12 (NR) | 11 LTP, 1MTP | Unicondylar | Posttraumatic | 50 (21-70) | 45.9 (27-105) |
| Ma et al., 2004 | 69 | RCS, level IV | OATS | Lysholm, Arthroscopy, XR | 2 (NR) | 2 LTP | 5 cm2 | Posttraumatic | 41 (32-51) | 46.5 (46-47) |
| Shasha et al., 2003 | 75 | RCS, level IV | OCA | HSS, XR | 65 (29 M/36 F) | 54 LTP, 11 MTP | Unicondylar | Posttraumatic | 42 (26-69) | 141.6 (60-288) |
| Ueblacker et al., 2004 | 56 | RCS, level IV | Retrograde OATS | Arthroscopy, XR, MRI | 3 (NR) | 2 LTP, 1 MTP | NR | 1 posttraumatic, 2 unknown | 38 (34-40) | 16 (6-35) |
| Wajsfisz et al., 2013 | 69 | PCS, level IV | OATS | IKDC, Tegner, KOOS | 4 (3 M/1 F) | 1 MTP, 3 LTP | 9 mm (8-10) | Posttraumatic | 31 (17-41) | 55 (52-60) |
| Yabumoto et al., 2017 | 75 | RCS, level IV | OATS | IKDC, Arthroscopy, ICRS, JOA, | 12 (6 M/6 F) | 3 MTP, 9 LTP | 220 mm2 (100-500) | 8 posttraumatic, 4 osteonecrosis | 38 (12-77) | 75 (24-126) |
OCS = osteochondral scaffold (Maioregen, Fin-Ceramica, Faenza, Italy) was a biomimetic nanostructured implant; OCA = osteochondral allograft; OATS = osteochondral autograft transfer system; ACI = autologous chondrocyte implantation; MTP = medial tibial plateau; LTP = lateral tibial plateau; DFO = distal femur osteotomy; HTO = high tibial osteotomy; IKDC = International Knee Documentation Committee; KS-F = Knee Society–Function; KSKS = Knee Society Knee Score; ICRS = International Cartilage Repair Society; JOA = Japanese Orthopaedic Association; KOOS = Knee injury and Osteoarthritis Outcome Score; VAS = visual analogue score; HSS = Hospital for Special Surgery; ROM = range of motion; XR = X-ray; MRI = magnetic resonance imaging; RCS = retrospective case series; PCS = prospective case series; M = male; F = female; DIC = disseminated intravascular coagulation; NR = not reported.
Includes additional patients without isolated tibial lesions.