Table 5.
Leptin/Adiponectin SF | Leptin/Adiponectin Serum | |||||||
---|---|---|---|---|---|---|---|---|
Univariate | Adjusted a | Univariate | Adjusted a | |||||
Nonobese PCC [95% CI] | Obese PCC [95% CI] | Nonobese PCC [95% CI] | Obese PCC [95% CI] | Nonobese PCC [95% CI] | Obese PCC [95% CI] | Nonobese PCC [95% CI] | Obese PCC [95% CI] | |
WOMAC pain | −0.125 [−0.398, 0.168] | 0.138 [−0.113, 0.373] | −0.284 [−0.553, 0.039]* | −0.043 [−0.307, 0.227] | 0.046 [−0.235, 0.321] | 0.198 [−0.050, 0.423] | −0.170 [−0.454, 0.145] | 0.113 [−0.157, 0.367] |
WOMAC function | −0.167 [−0.434, 0.126] | 0.331 [0.090, 0.535]*** | −0.292 [−0.559, 0.031]* | 0.120 [−0.153, 0.376] | 0.107 [−0.177, 0.374] | 0.223 [−0.024, 0.444]* | −0.061 [−0.362, 0.251] | 0.095 [−0.175, 0.351] |
WOMAC total | −0.173 [−0.438, 0.121] | 0.282 [0.037, 0.495]** | −0.300 [−0.566, 0.021]* | 0.071 [−0.201, 0.332] | 0.118 [−0.166, 0.384] | 0.210 [−0.038, 0.433]* | −0.056 [−0.357, 0.256] | 0.098 [−0.172, 0.354] |
TNF-α SF | 0.047 [−0.281, 0.366] | −0.114 [−0.364, 0.151] | −0.162 [−0.489, 0.204] | −0.147 [−0.406, 0.134] | 0.117 [−0.206, 0.417] | 0.174 [−0.088, 0.414] | 0.029 [−0.318, 0.368] | 0.210 [−0.066, 0.457] |
hsCRP SF | 0.191 [−0.113, 0.461] | 0.025 [−0.231, 0.277] | −0.006 [−0.325, 0.315] | −0.039 [−0.304, 0.231] | 0.144 [−0.149, 0.414] | 0.058 [−0.196, 0.306] | −0.011 [−0.317, 0.298] | 0.076 [−0.193, 0.335] |
IL-6 SF | −0.373 [−0.606, −0.082]** | −0.166 [−0.403, 0.092] | −0.475 [−0.692, −0.178]*** | −0.186 [−0.432, 0.086] | −0.030 [−0.318, 0.262] | 0.266 [0.015, 0.485]** | −0.057 [−0.362, 0.259] | 0.362 [0.106, 0.572]*** |
TNF-α serum | −0.092 [−0.379, 0.210] | −0.179 [−0.416, 0.081] | −0.030 [−0.346, 0.293] | −0.174 [−0.424, 0.102] | 0.009 [−0.279, 0.295] | 0.036 [−0.218, 0.285] | 0.125 [−0.189, 0.417] | 0.099 [−0.171, 0.355] |
hsCRP serum | 0.054 [−0.247, 0.345] | 0.215 [−0.044, 0.446] | −0.194 [−0.484, 0.134] | 0.125 [−0.150, 0.382] | −0.002 [−0.289, 0.285] | 0.171 [−0.084, 0.406] | −0.190 [−0.470, 0.125] | 0.128 [−0.142, 0.380] |
IL-6 serum | 0.225 [−0.077, 0.489] | 0.114 [−0.146, 0.360] | 0.091 [−0.235, 0.399] | 0.117 [−0.159, 0.375] | 0.199 [−0.094, 0.459] | 0.386 [0.149, 0.581]*** | 0.159 [−0.156, 0.445] | 0.450 [0.210, 0.639]**** |
SF = synovial fluid; WOMAC = Western Ontario and McMaster Universities Osteoarthritis Index; TNF-α = tumor necrosis factor–alpha; hsCRP = high-sensitivity C-reactive protein; IL-6 = interleukin-6.
The boldfaced entries are for statistically significant values.
Controlled for age, evolution time, body mass index, physical exercise, and Kellgren-Lawrence scale.
0.1 < P < 0.05, **P < 0.05, ***P < 0.01, ****P < 0.001.