Table 2.

Magnetic Resonance Imaging Features. ^a

WORMS Scores	Controls b (n = 168)	AKOA b (n = 106)	Adjusted Odds Ratio per 1 Unit Increase (95% CI)	P c,d
Cartilage (range 0-6)
Cartilage maximum (max)	2.5 (2, 3)	3 (2, 5)	1.18 (0.99-1.39)	0.062
PAT	2 (0, 3)	2.5 (1, 4.25)	1.08 (0.94-1.25)	0.270
TRO	0 (0, 2)	0.5 (0, 2.5)	0.98 (0.83-1.16)	0.830
MF	0 (0, 1)	0 (0, 2)	1.23 (0.99-1.54)	0.065
LF	0 (0, 0)	0 (0, 0)	1.18 (0.89-1.59)	0.272
MT	0 (0, 0)	0 (0, 0)	1.96 (1.19-3.24)	0.008
LT	0 (0, 1)	0 (0, 1)	1.08 (0.82-1.42)	0.600
Meniscus (range 0-4)
Bilateral meniscus max	2 (0, 2)	2 (1, 3)	1.37 (1.11-1.68)	0.003
Medial anterior horn	0 (0, 0)	0 (0, 0)	1.81 (0.67-4.83)	0.239
Medial body	0 (0, 0)	0 (0, 1)	1.37 (1.08-1.75)	0.010
Medial posterior horn	0 (0, 1)	1 (0, 1)	1.09 (0.85-1.41)	0.493
Lateral anterior horn	0 (0, 1)	0 (0, 1)	1.15 (0.89-1.47)	0.288
Lateral body	0 (0, 0)	0 (0, 1)	1.42 (1.08-1.87)	0.011
Lateral posterior horn	0 (0, 0)	0 (0, 1)	1.50 (1.10-2.05)	0.010
BMEP (range 0-3)
BMEP max	2 (0, 2)	2 (1, 2)	1.28 (1.00-1.64)	0.048
PAT	0 (0, 2)	1 (0, 2)	1.04 (0.81-1.34)	0.739
TRO	0 (0, 1)	0 (0, 1)	0.99 (0.75-1.30)	0.934
MF	0 (0, 0)	0 (0, 0)	1.36 (0.86-2.16)	0.187
LF	0 (0, 0)	0 (0, 0)	0.90 (0.44-1.87)	0.782
MT	0 (0, 0)	0 (0, 0)	1.69 (1.10-2.60)	0.016
LT	0 (0, 0)	0 (0, 0)	1.70 (1.12-2.61)	0.014

AKOA = accelerated knee osteoarthritis; BMEP = bone marrow edema pattern; PAT = patella; TRO = trochlea; MF = medial femur; LF = lateral femur; MT = medial tibia; LT = lateral tibia; WORMS = Whole-Organ Magnetic Resonance Imaging Score.

^aAssessed at index time point.

^bNumbers are median (25th and 75th percentiles).

^cSignificant values are in boldface.

^dMultivariable logistic regression adjusting for age, sex, body mass index, and race.