Table 3.

Description of fatal cases

Diagnosis	Gender	Age in years	Culprit drug(s)	Primary Comorbidities	Latent interval (in days)	Hospital Presentation (in days)	Casualty by ALDEN algorithm score and WHO-UMC scale	Complications	Treatment given as per protocol	Remarks
SJS	M	56	Nevirapine	HIV infection	23	3 days	Very Probable	Intracranial bleed and deep vein thrombosis right arm	Dexamethasone (i.v.) Supportive therapy	Died 1 week after hospital discharge. He had developed TEN after retaking nevirapine.
SJS	M	52	Nevirapine	HIV infection	30	4 days	Very Probable	Pneumonia, Respiratory distress	Dexamethasone (i.v.) Supportive therapy	Died on 2nd day of hospitalization
SJS	F	38	Allopurinol	CKD	19	20 days	Very Probable	Renal failure	Dexamethasone (i.v.) Supportive therapy Hemodialysis	Died on 10th day of hospitalization
TEN	F	26	Unknown	Major psychiatric disorder	Not known	3 days	Probable	Multi-organ failure ? sepsis	Dexamethasone (i.v.) Supportive therapy	Died after 12 days of hospitalization
Overlap	M	74	Sulfasalazine	Rheumatoid Arthritis	21	14 days	Very Probable	Multi-organ failure ? sepsis	Dexamethasone (i.v.) Supportive therapy	Died on 2nd day of hospitalization

*Drug re-challenge was not performed in any of the patients. ALDEN, algorithm of drug causality for epidermal necrolysis; CKD, chronic kidney disease; HIV, human immunodeficiency virus, SJS, Stevens-Johnson syndrome; TEN, toxic epidermal necrolysis; WHO-UMC, World Health Organization-Uppsala Monitoring Centre