Table 3.

CCV cargo proteins observed in podocytes

Protein Identifier	Protein Name	Exponentially Modified Protein Abundance Index	Mascot Score	NPXY	YXXø	[DE]XXXL[LI]	Literature
ANXA2	Annexin A2	9.67	1277	—	++	++	(28,29)
NUCL	Nucleolin	6.92	3069	—	++	Hsa	(30)
TSP1	Thrombospondin-1	3.01	2243	—	++	++	(31)
CTGF	Connective tissue growth factor	2.73	443	—	++	—	(32)
ITB1	Integrin β-1	1.84	858	++	++	++	(33,34)
GRB10	Growth factor receptor-bound protein 10	1.43	391	—	++	++	(35)
FINC	Fibronectin	1.4	2758	Mmu	++	++	(36,37)
LEG1	Galectin-1	1.28	101	—	—	—	(27)
MPRD	Cation-dependent mannose-6-phosphate receptor	1.22	485	—	++	Mmu	(38)
TFR1	Transferrin receptor protein 1	1.18	640	—	++	Mmu	(39)

Table of identified clathrin-coated vesicle cargo proteins ranked by abundance. Columns “NPXY,” “YXXø,” and “[DE]XXXL [LI]” show the presence of these cargo recognition motifs in respective protein sequences. “++” indicates presence in human and murine homologs; “Mmu” and “Hsa” indicate presence in a mouse or human homolog, respectively; and “—” indicates the absence of a cargo recognition motif.