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. Author manuscript; available in PMC: 2022 Feb 2.
Published in final edited form as: Alzheimers Dement. 2021 May 13;17(11):1798–1807. doi: 10.1002/alz.12367

Table 2.

Incidence of dementia events across categories of period-specific BMI, by sex, pooled CHS and Health ABC.

Women Men
Number of Events Person-years IR* 95% CI Number of Events Person-years IR* 95% CI
Overall 493 25581 416 20097
Early Adulthood BMI TWA (ages 20–49)
 <25 329 18377 15.9 14.1, 17.8 276 14298 19.0 16.6, 21.4
 25–30 115 5469 29.7 22.0, 37.2 114 5190 22.8 18.0, 27.7
 >30 49 1735 46.0 27.7, 64.3 26 609 44.6 26.0, 63.2
Midlife BMI TWA (ages 50–69)
 <25 215 9947 24.6 19.3, 29.9 129 6551 16.8 13.2, 20.4
 25–30 157 9611 17.8 14.7, 20.9 204 10070 22.0 18.8, 25.3
 >30 121 6023 15.1 10.6, 19.5 83 3476 26.2 17.4, 34.9
Late life BMI TWA (ages 70–89)
 <25 239 10895 22.0 18.8, 25.3 167 7006 29.4 24.0, 34.7
 25–30 163 9144 19.5 16.3, 22.6 191 9813 19.4 16.5, 22.2
 >30 91 5542 14.3 10.7, 17.9 58 3278 12.8 8.9, 16.6
*

IR: numbers of events per 1000 person-years at risk