Table 1.
Characteristics of Patients with T2DM and Controls
| Variable | Cases (n = 500) | Controls (n = 501) | p |
|---|---|---|---|
| Age (years, mean ± SD) | 59.87 ± 12.87 | 59.85 ± 9.34 | 0.973 |
| >60/≤60 | 240/260 | 268/233 | |
| Gender, Male/Female | 358/142 | 358/143 | 0.508 |
| BMI (kg/m2) <24/≥24 | 203/239 | 130/188 | |
| Unavailable | 58 | 183 | |
| Smoking, Yes/No | 219/280 | 98/164 | |
| Unavailable | 1 | 239 | |
| Drinking, Yes/No | 109/385 | 103/140 | |
| Unavailable | 6 | 258 | |
| T2DM duration (years) >10/≤10 | 193/307 | ||
| Fasting blood glucose (mmol/L) | 8.14 ± 3.35 | 5.65 ± 0.51 | <0.001 |
| Total cholesterol (mmol/L) | 4.18 ± 2.01 | 4.93 ± 4.00 | <0.001 |
| Triglyceride (mmol/L) | 1.91 ± 1.90 | 1.74 ± 0.97 | 0.088 |
| LDL-C (mmol/L) | 2.46 ± 0.90 | 2.61 ± 0.76 | 0.012 |
| HDL-C (mmol/L) | 1.05 ± 0.72 | 1.16 ± 0.55 | 0.024 |
| Urea (mmol/L) | 6.52 ± 3.26 | 5.42 ± 2.78 | <0.001 |
| Creatinine (μmol/L) | 71.20 ± 52.66 | 68.74 ± 12.87 | 0.322 |
| GFR (mL/min) | 96.62 ± 22.22 | 96.07 ± 19.78 | 0.710 |
| Serum uric acid (μmol/L) | 333.17 ± 99.15 | 318.33 ± 76.64 | 0.013 |
| Diabetic complications | |||
| Diabetic nephropathy | 146 | ||
| Diabetic retinopathy | 69 | ||
| T2DM with coronary heart disease | 126 | ||
| T2DM with hypertension | 269 | ||
Notes: p values were calculated by χ2 test for continuous variables and Student’s t test for categorical variables. Bold values indicate that p < 0.05 indicates statistical difference.
Abbreviations: T2DM, type 2 diabetes mellitus; BMI, body mass index; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; UCRP, ubiquitin cross-reactive protein.