Fig. 7. RAPA@Lipo@HMs reduce joint space narrowing and osteophyte formation.
(A) Representative x-ray images in anterior-posterior (AP) and lateral (LAT) view of the knee joint. (B) Representative micro-CT images in AP and LAT view of the knee joint. (C) The relative JSW measured from AP images. (D) The relative JSW measured from LAT images. (E) The relative osteophyte volume measured from micro-CT images (#, $, and * indicate P < 0.05 in comparison with the sham, RAPA@Lipo@HM, and PBS groups, respectively).