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. Author manuscript; available in PMC: 2022 Mar 1.
Published in final edited form as: Gut. 2021 May 7;71(3):487–496. doi: 10.1136/gutjnl-2020-322873

Figure 4.

Figure 4

Analysis of ileal lamina propria CD4+ T cells of IgA−/−. (A) Flow cytometric analysis of the ileal lamina propria lymphocytes of WT (left) and IgA−/− (right). B220−CD3+ cells were gated and then opened by CD3 and CD4. Representative data from each group are shown. (B) The ratios of stained CD3+ and CD4+ T cells from the lamina propria of WT (left), IgA−/− (middle) and ABx-treated IgA−/− (right). Data are expressed as means±SEM. (n>3). *p<0.05. **p<0.01. (C–F) Cytokine production from the ileal lamina propria CD4+ T cells of WT (left), IgA−/− (middle) and ABx-treated IgA−/− (right) after stimulation with anti-CD3e and anti-CD28 Abs. The concentrations of IFN-γ (C), IL-17 (D), IL-4 (E) and IL-10 (F) in culture supernatants were determined (n>3). Values are presented as means±SEM (n>3). N.S., not significant. *p<0.05.