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. 2022 Feb 2;8(5):eabm0142. doi: 10.1126/sciadv.abm0142

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Fig. 3. — Flow cytometry of neutrophil (A) and inflammatory monocyte (B) recruitment to the kidneys of Dpep1^+/+ and Dpep1^−/− at 24 hours (circles) and 48 hours (squares) after IRI. Contralateral (Cntrl) kidneys are used as controls. [Neutrophils: Dpep1^+/+ (24 hours) Cntrl versus IRI, **P = 0.005; IRI (24 hours) Dpep1^+/+ versus Dpep1^−/−, **P = 0.008; Dpep1^+/+ (48 hours) Cntrl versus IRI, **P = 0.006; IRI (48 hours) Dpep1^+/+ versus Dpep1^−/−, ***P = 0.001; n = 5 per group, Student’s t test.] [Monocytes: Dpep1^+/+ (24 hours) Cntrl versus IRI, ***P = 0.001; IRI (24 hours) Dpep1^+/+ versus Dpep1^−/−, **P = 0.004; Dpep1^+/+ (48 hours) Cntrl versus IRI, **P = 0.004; IRI (48 hours) Dpep1^+/+ versus Dpep1^−/−, ns = not significant; n = 5 per group, Student’s t test.] Flow cytometry of neutrophil (C) and inflammatory monocyte (D) recruitment to the kidneys of LSALT peptide–treated mice at 24 hours (circles) and 48 hours (squares) after IRI. Contralateral (Cntrl) kidneys are used as controls. [Neutrophils: Cntrl versus IRI (24 hours), **P = 0.005; IRI (24 hours) no treatment versus LSALT, **P = 0.01; Cntrl versus IRI (48 hours), *P = 0.048; IRI (48 hours) no treatment versus LSALT, *P = 0.04; n = 6 to 8 per group, Student’s t test.] [Monocytes: Cntrl versus IRI (24 hours), ***P = 0.0003; IRI (24 hours) no treatment versus LSALT, **P = 0.005; Cntrl versus IRI (48 hours), **P = 0.002; IRI (48 hours) no treatment versus LSALT, *P = 0.047; n = 5 to 8 per group, Student’s t test.]