Figure 1.

Distinct expression patterns of E2F2 and mir-125a-5p were observed in traumatic OA cartilage. A, Possible targeting relationship within mir-125a-5p and E2F2 was given by targetscan and Starbase databases. B, Verification of dual luciferase assay on the targeting relationship within mir-125a-5p and E2F2. C, Determination with RT qPCR assay on the expression of mir-125a-5p and E2F2 in normal cartilage and traumatic OA cartilage. D, Western blot was conducted to determinate the E2F2 expression in normal cartilage and traumatic OA cartilage. ** means P < 0.01, compared with normal group or mimics NC transfected cells