Figure 2.

Si-circ-PSEN1 regulates contents of GSH, Fe²⁺, and MDA in the HG-treated ARPE19 cells. (a) The expression levels of circ-PSEN1 when the ARPE19 cells were transfected with si-circ-PSEN1 1# and si-circ-PSEN1 2#. (b) GSH, (c) MDA, and (d) Fe²⁺ contents were examined in the HG-treated cells 48 h after transfection with si-circ-PSEN1 using the corresponding kits. Data are representative of three experiments; *P < 0.05; **P < 0.01. HG, high glucose; ARPE19, adult retinal pigment epithelial cell line-19; GSH, glutathione; MDA, malondialdehyde