Figure 3.

Simvastatin induces miR-19a-3p expression in AML cells to regulate the proliferation, apoptosis, migration and invasion. (a) qRT-PCR served to identify miR‐19a‐3p mRNA of AML cell lines. (b) Cell viability was analyzed by CCK-8. (c) Apoptosis analysis was identified through Flow Cytometry. (d) Apoptosis protein levels were performed by WB. (e) The migration and invasion were observed by transwell and wound healing. Compared with control group, *P < 0.05, **P < 0.01. Compared with the simvastatin group, ^#P < 0.05, ^##P < 0.01