Figure 3.

Down-regulated miR-934 suppressed cell migration and invasion in colorectal cancer cell lines. (a) Wound healing assay was performed to measure migration ability of HCT116 and SW480 cells after miR-934 knockdown. Scale bar: 200 μm. (b) Transwell assay was conducted to detect the invasive capacity of HCT116 and SW480 cell line after t after miR-934 knockdown. Scale bar: 100 μm. (c) The protein levels of MMP-9 and MMP-2 were respectively determined by western-blot analysis in HCT116 and SW480 cells after miR-934 knockdown. Bars and error bars represent mean values and the corresponding SD, n = 3. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001