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. 2021 Dec 2;12(2):10761–10770. doi: 10.1080/21655979.2021.2003130

Figure 2.

Figure 2.

TSPAN1 contributes to the growth and motility of breast cancer cells. (a). CCK-8 assays showed the growth capacity of MCF-7 and SK-BR-3 cells upon the transfection of control or TSPAN1 siRNAs. (b). Wound closure assays showed the migration capacity of MCF-7 and SK-BR-3 cells upon the transfection of control or TSPAN1 siRNAs. The quantification of panel B, and the wound width was measured. (c). Colony formation assays confirmed the effects of TSPAN1 on the proliferation of MCF-7 and SK-BR-3 cells. (d). Transwell assays showed the invasion capacity of MCF-7 and SK-BR-3 cells upon the transfection of control or TSPAN1 siRNAs. Data are shown as mean ± SEM, *p < 0.05, **p < 0.01