Figure 2.

Fer-1 inhibited LPS-induced ferroptosis in myocardium. (a, b) Representative western blots and statistical analysis of expression of GPX4 in four groups of rats (n = 3 per group). (c, d) Representative western blots and statistical analysis of expression of PTGS2 in four groups of rats (n = 3 per group). Data are expressed as mean ±SEM. *P < 0.05 vs. Control group, #P < 0.05 vs. LPS group

Abbreviations: Fer-1, Ferrostatin-1; LPS, Lipopolysaccharide; GPX4, Glutathione peroxidase 4; PTGS2, Prostaglandin endoperoxide synthase 2.