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. 2021 Nov 22;12(2):9332–9340. doi: 10.1080/21655979.2021.2000742

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© 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — STM reduces cell damage in IL-1β-induced ATDC5 cells via SREBF2

(a) The SREBF2 protein expression was detected by Western blotting. (b) The SREBF2 mRNA expression was detected by RT-qPCR. (c) The protein levels of IL-6, TNF-α and IL-10 were detected by using Western blotting. (d) The levels of MDA, SOD and GSH were detected by using the corresponding kits. (e) The expression levels of collagen X, MMP13, collagen II and aggrecan were detected by Western blotting. ***p < 0.001 vs. Control; ^###p < 0.001 vs. IL-1β; ^&p < 0.05, ^&&p < 0.01 and ^&&&p < 0.001 vs. IL-1β+STM+Oe-NC.