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Zafirlukast ameliorated Docetaxel-induced oxidative stress in LO-2 hepatocytes. Cells were stimulated with Docetaxel (20 μM) in the presence or absence of Zafirlukast (5, 10 μM) for 24 hours. (a). The levels of 8-OHdG; (b). The levels of reduced GSH; (c). The levels of ROS generation (####, P < 0.0001 vs. control group; **, ***, P < 0.01, 0.005 vs. Docetaxel group)
