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The mechanism of miR-140-5p affecting chondrocyte pyroptosis and repairing OA. miR-140-5p was overexpressed in the murine model of OA by agomiR-140-5p injection, thus inhibiting CTSB transcription, further repressing the binding of CTSB and NLRP3, reducing chondrocyte pyroptosis, and alleviating cartilage injury in OA
