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. 2021 Dec 19;12(2):11909–11921. doi: 10.1080/21655979.2021.2006551

Figure 5.

Figure 5.

Activating PI3K repressed the effect of ITGA11 knockdown on GC progression

ITGA11 knockdown plasmids and/or IGF-1 were added to MKN45 cells. A-B: The CCK-8 assay and colony formation test were carried out to gauge cell proliferation. C-D: Cell migration and invasion were assessed by Transwell assay. E: The profiles of Bcl-2 and Bax were monitored by WB. F: WB gauged the protein levels of the PI3K/AKT axis in MKN45 cells. * P < 0.05, * * P < 0.01, * * * P < 0.001, N = 3