Figure 6.

Knocking down ITGA11 dampened GC cell growth cells in vivo.

Mouse tumor models knocking down ITGA11 were constructed in MKN45 and AGS cell lines. A: Analysis of survival rates in mice. B-G: After 30 days, the nude mice were sacrificed, and their subcutaneous nodules were removed, with tumor volume and weight calculated. H: The TUNEL assay was employed to examine apoptosis in tumor tissues. I: The fluorescence intensity of the PI3K/AKT pathway was checked by tissue immunofluorescence. J: The profiles of ITGA11 and PI3K/AKT were tested by WB. * * * P < 0.001, N = 5