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. 2021 Dec 11;12(2):12394–12406. doi: 10.1080/21655979.2021.2005217

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© 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — miR-543 had a negative effect on cell migration and invasion in breast cancer. (a) Cell migration was detected by wound healing assay. (b) Cell invasion was detected by transwell invasion assay. (a-b) *P < 0.05, **P < 0.001 versus blank control group. Blank: blank control. NC: negative control. mimic: miR-543 mimic. (c) Subcutaneous tumors in nude mice derived with MDA-MB-231 cells transfected with miR-543 agomir and NC agomir. (d) tumor volumes of the subcutaneous tumors. **P < 0.001. NC: negative control