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. 2021 Nov 29;12(2):11154–11166. doi: 10.1080/21655979.2021.2005982

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© 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — SERPINC1 is downregulated in serum of VTE rats

(a) Representative images for gross IVC with thrombus obtained from rats at indicated time point (6 h, 12 h, 24 h, and 48 h post IVC ligation). (b) Thrombus weight, (c) D-dimer serum level and (d) TAT serum level from control and thrombotic rats at indicated time points. n = 6. (e-f) SERPINC1 mRNA level and protein level in control or thrombotic group at indicated time points was examined using RT-qPCR and western blotting, respectively. n = 6. (g) Scatter plot analysis of the correlation between SERPINC1 level and thrombus weight of rats in the thrombotic group. n = 24. *p < 0.05, **p < 0.01, ***p < 0.001.