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. 2021 Nov 29;12(2):11154–11166. doi: 10.1080/21655979.2021.2005982

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© 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 5. — SERPINC1 expression is negatively related to miR-200c-3p level in plasma of VTE patients

(a) Circulatory miR-200 c-3p level and (b) SERPINC1 protein level in plasma of VTE patients (n = 47) and control subjects (n = 14). (c) Scatter plot analysis of the correlation between SERPINC1 protein level and miR-200 c-3p expression in plasma of VTE patients. n = 47. **p < 0.01.Graphic abstract: miR-200 c-3p targets SERPINC, the gene for antithrombin, to reduce SERPINC1 translation, ultimately alleviating the aggravation of VTE.