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Model refinement statistics
| Fab:CGRP | Fab | |
|---|---|---|
| Refinement resolution (Å) | 48.57–3.10 | 45.14–1.54 |
| Rcryst (%) | 18.05 | 15.9 |
| Rfree (%) | 26.58 | 19.0 |
| Protomer details (per asymmetric unit) Eptinezumab Fab CGRP |
2 2 |
1 ‒ |
| Bond lengths, rms (Å) | 0.005 | 0.016 |
| Bond angles, rms (°) | 1.467 | 1.99 |
| Ramachandran plot (%) Preferred Allowed Outliers |
86.9 9.9 3.2 |
97.4 2.6 0.0 |
Abbreviations: CGRP, calcitonin gene-related peptide; Fab, antigen-binding fragment
