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Effect of nanoparticle sizes on the pharmacokinetics. (a) Concentration of nanoparticles with different size in the mice serum after the injection within 48 hours. (b)The terminal half-time (T1/2), (c) area under the serum concentration–time curve (AUC(0–48 h)) and (d) clearance (CLZ) as pharmacokinetics parameters were analyzed. Data were mean ± s.d. from n = 3 independent experiments
