Figure 4.

FBXL11 is upregulated in BC and related to poor prognosis. (a) RT-qPCR of the expression of FBXL11 in 20 pairs of BC and normal tissues. (b-c) Western blotting of the protein level of FBXL11 is 20 pairs of BC and normal tissues. Protein bands of the other 19 samples are provided in the supplementary file named Figure S1. (d) The relationship between FBXL11 level and BC patients’ prognosis examined by Kaplan-Meier Plotter. (e) The association between the expressions of NSD1 and FBXL11 in BC samples examined by GEPIA database. (f) RT-qPCR analysis of FBXL11 expression in MCF-7 and MCF-7/PR cells. (g) Western blotting of FBXL11 protein expression in BC cells. (h) CCK-8 assay for examining cell viability of MCF-7/PR with FBXL11 silencing. *p < 0.05.***p < 0.001