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MiR-191-5p is downregulated in the hippocampal tissues of APP/PS1 mice. (a-b) Pathological changes of the hippocampus in C57BL/6 J mice and APP/PS1 mice were assessed by H&E staining and Nissl staining. (c) Aβ-positive granules in the hippocampal tissues of C57BL/6 J mice and APP/PS1 mice were determined by immunohistochemical staining. (b) MiR-191-5p expression in the hippocampal tissues of C57BL/6 J mice (n = 8) and APP/PS1 mice (n = 24) was detected by RT-qPCR. ***p < 0.001
