TCMSP |
Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform |
GO |
Gene Ontology |
KEGG |
Kyoto Encyclopedia of Genes and Genomes |
PPI |
protein-protein interaction |
OB |
oral bioavailability |
DL |
drug-likeness |
BBB |
blood-brain-barrier |
TTD |
Therapeutic Target Database |
MCC |
maximal clique centrality |
MNC |
maximum neighborhood component |
BP |
biological processe |
CC |
cellular component |
MF |
cellular component |
DMEM |
Dulbecco’s Modified Eagle Medium |
CNS |
Canadian Neurological Scale |
MMSE |
Mini-Mental State Examination |
qRT-PCR |
Quantitative reverse-transcription polymerase chain reaction |
DAVID |
Database for Annotation, Visualization and Integrated Discovery |
IL-1β |
interleukins-1β |
TNF |
tumor necrosis factor |
MAPK |
Mitogen-activated protein kinase |
ERK |
extracellular signal-regulated kinase |
JNK |
c-Jun NH2-terminal kinase |
MMP |
Matrix metalloproteinase |
PTGS2 |
Prostaglandin H synthase 2 |
COX |
cyclooxygenase |
PGE2 |
prostaglandin E2 |
MCAO |
middle cerebral artery occlusion |
SGLT-1 |
sodium-glucose transporter type 1 |
OGD |
oxygen and glucose deprivation |