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. 2021 Dec 19;12(2):12274–12293. doi: 10.1080/21655979.2021.2006966
TCMSP Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform
GO Gene Ontology
KEGG Kyoto Encyclopedia of Genes and Genomes
PPI protein-protein interaction
OB oral bioavailability
DL drug-likeness
BBB blood-brain-barrier
TTD Therapeutic Target Database
MCC maximal clique centrality
MNC maximum neighborhood component
BP biological processe
CC cellular component
MF cellular component
DMEM Dulbecco’s Modified Eagle Medium
CNS Canadian Neurological Scale
MMSE Mini-Mental State Examination
qRT-PCR Quantitative reverse-transcription polymerase chain reaction
DAVID Database for Annotation, Visualization and Integrated Discovery
IL-1β interleukins-1β
TNF tumor necrosis factor
MAPK Mitogen-activated protein kinase
ERK extracellular signal-regulated kinase
JNK c-Jun NH2-terminal kinase
MMP Matrix metalloproteinase
PTGS2 Prostaglandin H synthase 2
COX cyclooxygenase
PGE2 prostaglandin E2
MCAO middle cerebral artery occlusion
SGLT-1 sodium-glucose transporter type 1
OGD oxygen and glucose deprivation