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. 2022 Feb 3;2(2):92–102. doi: 10.1016/j.jointm.2021.12.003

Table 1.

Evaluation of the quality of respiratory support decision implementation.

Item Code Score Scoring criteria Score
Yes No
Prevention of fatal situation and emergency intubation A 1 Avoid fatal hypoxia or hypercapnia (SO2 < 70% or RR < 8 times/min or PaCO2 > 50 mmHg)
OR
Intubate and IMV in time (no >1 h when fatal hypoxia or hypercapnia happens)
B 1 Avoid fatal respiratory distress (RR > 40 times/min or loss of consciousness or blood lactic acid >4 mmol/L)
OR
Intubate and IMV in time (no >1 h when fatal respiratory distress happens)
Traditional and HFNC oxygen therapy management and intubation timing C 1 FiO2 ≤ 70% to maintain the target SO2
OR
Intubate and IMV in <12 h when the FiO2 > 70%
D 1 RR ≤ 35 times/min
OR
Intubate and IMV in <6 h when RR > 35 times/min
NIV management and intubation time E 1 FiO2 ≤ 70% to maintain the target SpO2
OR
Intubate and IMV in <12 h when the FiO2 > 70%
F 1 RR ≤ 30 times/min
OR
Intubate and IMV in <6 h when RR > 30 times/min
Lung protective ventilation strategy G 1 Vt ≤ 8 mL/kg (ideal body weight)
H 1 Pplat ≤ 30 cmH2O
OR
Pplat down to 30 cmH2O within 24 h when Pplat > 30 cmH2O
I 1 Driving pressure ≤15 cmH2O
OR
Driving pressure down to 15 cmH2O within 24 h when driving pressure >15 cmH2O
NMBAs administration J 1 Avoid PaO2/FiO2 < 150 mmHg
OR
Using NMBAs for the IMV with PaO2/FiO2 < 150 mmHg in 48 h after intubation for 48–72 h
Prone position K 1 Avoid PaO2/FiO2 < 100 mmHg
OR
Prone position >12 h/day for IMV patients with PaO2/FiO2 < 100 mmHg
Ventilation effect at 48 h after intubation by fine adjustment L 1 Achieved PaO2/FiO2 increases >20%
M 1 Achieved PaCO2 < 48 mmHg
N 1 Achieved Cstat of lungs >30 mL/cmH2O
ECMO initiation and MV management during ECMO O 2 Avoid ECMO
OR
Decision of initiating ECMO in time, including
PaO2/FiO2 < 50 mmHg over 3 h or PaO2/FiO2 < 80 mmHg over 6 h
Arterial blood gas pH < 7.25 and PaCO2 > 60 mmHg over 6 h, as well as RR over 35 times/min
RR > 35 times/min, arterial blood gas pH < 7.2 and plateau pressure >30 cmH2O
Complicated with cardiogenic shock or cardiac arrest
P 1 Avoid ECMO
OR
Make right super protective ventilation strategy, including drive pressure ≤15 cmH2O and PEEP ≤ 10 cmH2O
Respiratory drive management during IMV Q 1 Avoid RR > 30 times/min lasts >6 h
Deduction R −2 SO2 < 80% lasts >6 h during hospitalization
S −2 Ineffective RM were performed for more than twice;
OR
The duration of high PEEP that resulted in decreased lung compliance exceeded 12 h
T −2 ECMO implementation after 7 days of IMV

Cstat: Static compliance; ECMO: Extracorporeal membrane oxygenation; FiO2: Fraction of inspired oxygen; HFNC: High-flow nasal cannula; IMV: Invasive mechanical ventilation; NIV: Non-invasive ventilation; NMBAs: Neuromuscular blocking agents; PaCO2: Partial pressure of carbon dioxide; PaO2: Partial pressure of arterial oxygen; PEEP: Positive end-expiratory pressure; Pplat: Plat pressure; RM: Recruitment maneuver; RR: Respiratory rate; SO2: Oxygen saturation.