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. 2021 Dec 9;602(7895):106–111. doi: 10.1038/s41586-021-04288-3

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 4 — For each sample (points) and each of the three HbS-associated loci (rows), the figure shows the proportion of sequencing reads that carry the nonreference allele (y axis). Points are separated by country (columns) and HbS genotype (x axis); the x axis values are jittered to visually separate. The called Pf genotype of each sample is indicated by the shape, with mixed calls indicated by squares.