Figure 3.
Comparison of tissue dependent MHCI-associated (Mouse) and HLAI (Human) -associated peptides
(A) MHCI peptide counts for each sampled mouse tissue, colors depict the MHCI alleles (H2Db and H2Kb).
(B) HLAI peptide counts for all sampled human tissues. Boxplots are represented as several tissues were sampled across different individuals.
(C) Comparison of MHCI peptide counts/tissue (Mouse) and HLAI peptide counts/tissue (Human).
(D) Principal component analysis of the measured intensities (log10) of MHCI peptides (Mouse).
(E) Principal component analysis of the measured intensities (log10) of HLAI peptides (Human).
(F) Tissue connectivity map of the ‘B57BL/6 MHCI Ligand atlas. Heatmap depicts the number of shared MHCI peptides across tissues (Mouse). Note: The number of uniquely observed/tissue-specific peptides can be found along the diagonal. Spinal cord (mouse) and Myelon (human) are equivalent terms