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. 2022 Feb 3;14:100966. doi: 10.1016/j.cegh.2022.100966

Table 2.

Table showing the case studies of the individual patients having Post COVID-19 MIS-C.

Sl. No. Region Schedule of patient admission Patient's description Symptoms and image findings Laboratory findings Similarities with Treatment Reference
1. Atlanta, Georgia June 2020 A 25-year-old woman Exhaustion, dyspnea, mild cough and low-grade fevers, vomiting, sore throat, diarrhoea, slight hypotension (blood pressure 98/56 mmHg) and usual blood oxygen level in indoor air, cervical lymphadenopathy; notable conjunctival injection; red and cracked lips; left lower abdominal tremble.
Echocardiogram: Enlarged inferior vena cava, cardiac dysfunction.
CT of abdomen/pelvis: Stranding of peri-pancreatic fat; pancreatitis, indefinite bilateral perinephric fat stranding.
Troponin-I was discovered at 0.06 ng/mL; high levels of creatinine (7.74 mg/dL), BNP (378 pg/ml), d-dimer (960 ng/ml), ferritin (798 ng/ml). KD To minimize the chances of thromboembolic and nephrotoxicity, IVIG (2 g/kg) was administered in uniform dosages on the second and third day of the hospital admission, along with aspirin (325 mg) for 7 days, and redeliver. 9
2. New York May 2020 An 11-year-old female Initial: sore throat, uneasiness, low appetite, leg and abdominal pain, pruritus skin rash, fever (39.3 °C), tachycardia (126beats/minute), hypotension, slight dehydration, erythematous palm with a widespread reticular, non-blanching papular rash across the belly and bilateral upper extremities.
Echocardiogram: Decreased systolic function of the left ventricle.
Electrocardiogram: Showed sinus tachycardia and S1Q3T3 indicating strain on the right side of the heart.
Uplifted levels of troponin (0.112 ng/mL) and BNP (8718 pg/mL). White blood cell count increased to 14.18 causing lymphopenia. PTT yielded an increased value of 1.9 along with the raised levels of IL-6 (0.0–15.5 pg/mL), ferritin (13.00–150.00 ng/mL), D-dimer (0–243 ng/mL, procalcitonin (0.00–0.50 ng/mL), CRP (0.10–2.80 mg/L) and normal level of creatinine (0.53–0.79 mg/dL). TSS, septic shock, cytokine storm, KD, SHLH Furosemide along with antibiotics like clindamycin, ceftaroline, and piperacillin-tazobactam was administered. Enoxaparin was started as a comprehensive anticoagulant. Vitamin K was employed to improve elevated INR and PT. An IL-6 blocker, tocilizumab, was progressed along with convalescent plasma therapy and remdesivir. 45
3. Not found Not found A 14-year-old boy Fever, tachycardia and inflamed maculopapular rash on the face, abdominal sensitivity, as well as a perianal injurydischarging pus. A 28-cm ileitis, a 2.3-cm perianal pustule, and a fistula were diagnosed on magnetic resonance enterography. Initially, tests revealed a normal ESR rate (0–5 mg/L) and normal levels of CRP (0–15 mm/h). Increased serum amounts of IL-6 (73.4 pg/mL), IL-8 (21.8 pg/mL), IL-1β (0.4 pg/mL), TNF-α (97.8 pg/mL) were noticed in the cytokine profile up to eight days of hospitalization, which later on declined till the tenth day on treatment with infliximab. KD Azithromycin and hydroxychloroquine were used for SARS-CoV-2 infection, intravenous piperacillin/tazobactam was used to cure perianal abscess, and enoxaparin was utilized for the prevention of venous thromboembolism, along with intravenous fluid therapy. 51
4. Kerala, India April 2020 A 5-year-old boy Fever of high intensity, abdominal cramps and watery stools, pyuria, bulbar conjunctivitis without pus and non-pitting edema of the feet and hands, tachycardia (130 beats per min), vasoplegia.
Echocardiogram: Comprehensive left ventricular hypokinesia with medium systolic dysfunction (EF = 35%) and myocarditis was discovered.
Chest X-ray: Disclosed cardiomegaly.
Inflammatory cytokines in blood serum-like CRP, ferritin, creatinine and liver enzymes were found to be upraised. The results of a complete blood count revealed neutrophilic leucocytosis. KD Pulmonary support using a high flow nasal cannula with a 2 L/kg flow rate was attempted, as well as inotropic support was provided with adrenaline; Ceftriaxone, an injectable antibiotic, immunoglobulins, diuretic drugs, enalapril and methylprednisolone pulse (30 mg/kg/d for 3 d), were some of the remedies. 47