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. 2022 Jan 20;11:811941. doi: 10.3389/fonc.2021.811941

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Copyright © 2022 Srivastava, Sharma, Khanna, Sadhu Balasundaram, Chowdhury, Chowdhury and Mukherjee

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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IL-6 induces pro-proliferative effects in Huh-7 cells. (A) Analysis of cell viability after 48 or 72 h post-IL-6 (25 ng/ml) exposure. (B) Phase-contrast and crystal violet stained images of untreated or IL-6-treated (25 ng/ml) cells at 72 h (scale bar: 100 μm). (C) Transcript levels of Ki67 and PCNA and protein level of PCNA after IL-6 treatment (25 ng/ml) for 72 h (D) The transcript level of IL-6R after IL-6 treatment for 72 h. ** and *** refers to p value significance of ≤0.01 and ≤0.001 respectively.